Mansoor AlNaim
King Abdulaziz National Guard Hospital , Saudi Arabia
Biography
Background:
Diabetes mellitus type 2 is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin [1]. Hypothyroidism, also called underactive thyroid or low thyroid, is a common disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone [2]. Thyroid diseases and diabetes mellitus are the two most common endocrine disorders encountered in clinical practice [3]. Hyper- and hypothyroidism have been associated with insulin resistance, which has been reported to be the major cause of impaired glucose metabolism in diabetes mellitus type 2 [4].
Objectives:
General Objective:
The main aim of this study to investigate the prevalence of Hypothyroidism among patient with type two diabetes mellitus in security forces hospital Riyadh – Kingdom of Saudi Arabia.
Specific objectives:
Determine the correlation between Hypothyroidism and following factors; Age, Gender, Body Mass and Chronic Diseases.
Method:
A retrospective cross-sectional study was done on 300 patients who diagnosed with type 2 diabetes and regularly attended the diabetic center for care for one year at security forces hospital, Riyadh, Saudi Arabia. All patients underwent a clinical and laboratory evaluation.
Results:
Out of 300 randomly selected type 2 diabetic patients with hypothyroidism; 82% have TSH level ranged between 0.5 to 5.0 µIU/dl (group1), 13% have TSH level > 5.0 µIU/dl (group 2) and 5% were missed data. A statistically significant association existed between BMI and HbA1c l level and TSH level. However, Age, Blood pressure, Fasting blood glucose, Low-density lipoprotein, High-density lipoprotein, Triglyceride and Cholesterol were not significantly associated with the TSH level. In addition, there was a statistically significant association between HbA1C level and type of treatment received by our population but Fasting blood glucose level was not significant. Regarding the TSH level, out of 285 patients; 9.5% were diagnosed normal and 90.5% were diagnosed abnormal regarding to the TSH level.